Lipogenesis in Fatty Liver by Amino Acid Imbalance
نویسندگان
چکیده
منابع مشابه
Amino acid imbalance in cystinuria.
After oral ingestion of a free amino acid mixture by three cystinuric patients, plasma increments of lysine and arginine were lower and those of many other amino acids were significantly higher than those found in control subjects. Similar results were obtained in control subjects after amino acid imbalance had been artificially induced by the omission of cystine, lysine, and arginine from the ...
متن کاملFatty acid metabolism and hepatic lipogenesis.
The conversion of octanoate-l-Cl4 to radioacetoacetate and the effect of pyruvate on this process are dependent on the K+ concentration in the incubation medium (1). These results prompted this investigation in which the incorporation of octanoate-l-Cl4 into fatty acids and cholesterol was determined in the presence of non-radioactive additions of pyruvate, succinate, and fumarate. Malonate was...
متن کاملAltered interactions between lipogenesis and fatty acid oxidation in regenerating rat liver.
The concentrations of malonyl-CoA, citrate, ketone bodies and long-chain acylcarnitine were measured in freeze-clamped liver samples from fed or starved normal, partially hepatectomized or sham-operated rats. These parameters were used in conjunction with measurements of the concentration of plasma non-esterified fatty acids and the rates of hepatic lipogenesis to obtain correlations between ra...
متن کاملPalmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis.
BACKGROUND Biochemical evidence has linked the coordinate control of fatty acid (FA) synthesis with the activity of stearoyl-CoA desaturase-1 (SCD1). The ratio of 16:1n-7 to 16:0 [SCD1₁₆] in plasma triacylglycerol FA has been used as an index to reflect liver SCD1₁₆ activity and has been proposed as a biomarker of FA synthesis, although this use has not been validated by comparison with isotopi...
متن کاملAmino acid imbalance and nitrogen retention.
It is 12 years since Krehl and coworkers (1, 2) reported that the growth of young rats fed on low protein diets deficient in niacin and tryptophan was retarded when a tryptophan-deficient protein supplement such as gelatin or zein was added to the diet, and that the growth retardation was prevented if additional tryptophan was provided. In the interval, amino acid imbalances involving practical...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1972
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.36.1159